Bolder BioTechnology, Inc. Protein Image


Publications


Heinzelman, P., Carlson, S.J., and Cox, G.N. (2015)
Cytokine refacing effect reduces granulocyte-macrophage colony-stimulating factor susceptibility to antibody neutralization. Protein Engineering Design and Selection 28: 461-466, 2015.

Fam, C.M., Eisenberg, S.P., Carlson, S.J., Chlipala, E.A., Cox, G.N. and Rosendahl, M.S. (2014)
PEGylation improves the pharmacokinetic properties and ability of interferon gamma to inhibit growth of a human tumor xenograft in athymic mice. Journal of Interferon and Cytokine Research 34: 759- 768.

Cox, G.N., Chlipala, E.A., Smith, D.J., Carlson, S.J., Bell, S.J. and Doherty, D.H. (2014)
Hematopoietic properties of granulocyte colony-stimulating factor/immunoglobulin fusion proteins (G-CSF/IgG-Fc) in normal and neutropenic rodents (2014) PLOS ONE Mar 17;9(3):e91990. doi: 10.1371/ journal.pone.0091990.

Plett, P.A., Chua, H.L., Sampson, C.H., Katz, B.P., Fam C.M., Anderson, L.A., Cox, G.N., and Orschell C.M. (2014)
PEGylated G-CSF (BBT-015), GM-CSF (BBT- 007), and IL-11 (BBT-059) analogs enhance survival and hematopoietic cell recovery in a mouse model of the hematopoietic syndrome of the acute radiation syndrome. Health Physics Journal 106: 7-20.

Lee. J.I., Eisenberg, S.P, Rosendahl, M.S., Chlipala, E.A., Brown, J.D., Doherty, D.H., and Cox G.N. (2013)
Site-specific PEGylation enhances the pharmacokinetic properties and anti-tumor activity of Interferon Beta-1b. Journal of Interferon and Cytokine Research 33: 769-777.

Lee, H.T., Park, S.W., Kim, M., Ham, A., Kim, J.Y., Anderson, L.J., Brown, K.M., D'Agati, V.D. and Cox, G.N. (2012)
Interleukin-11 protects against renal ischemia and reperfusion injury. American Journal of Physiology - Renal Physiology 303: F1216-1224.

Bell , S.J., Fam, C.M., Chlipala, E.A., Carlson, S.J., Lee, J.I., Rosendahl, M.S., Doherty, D.H. and Cox, G.N. (2008)
Enhanced circulating half-life and anti-tumor activity of a site-specific pegylated interferon- a protein therapeutic. Bioconjugate Chemistry 19: 299-305.

Cox, G.N., Rosendahl, M.S., Chlipala, E.A., Smith, D.J., Carlson, S.J. and Doherty, D.H. (2007)
A long-acting, monoPEGylated human growth hormone analog is a potent stimulator of weight gain and bone growth in hypophysectomized rats. Endocrinology 148: 1590-1597.

Long, D.L., Doherty, D.H., Eisenberg, S.P., Smith, D.J., Rosendahl, M.S., Christensen, K.R., Edwards, D.P., Chlipala, E.A., and Cox, G.N. (2006)
Design of homogeneous, monoPEGylated erythropoietin analogs with preserved in vitro bioactivity. Experimental Hematology 34: 697-704.

Doherty, D.H., Rosendahl, M.S., Smith, D.J., Hughes, J.M., Chlipala, E.A. and Cox, G.N. (2005)
Site-specific PEGylation of engineered cysteine analogues of recombinant human granulocyte-macrophage colony-stimulating factor. Bioconjugate Chemistry 16: 1291-1298.

Rosendahl, M.S., Doherty, D.H., Smith, D.J., Bendele, A.M. and Cox, G.N. (2005)
Site-specific protein PEGylation: application to cysteine analogs of recombinant human granulocyte colony-stimulating factor. BioProcess International 3: 52-62.

Rosendahl, M.S., Doherty, D.H., Smith, D.J., Carlson, S.J., Chlipala, E.A. and Cox, G.N. (2005)
A long-acting, highly potent interferon α-2 conjugate created using site-specific PEGylation. Bioconjugate Chemistry 16: 200-207.

Cox, G.N., Smith, D.J., Carlson, S.J., Bendele, A.M., Chlipala, E.A. and Doherty, D.H. (2004)
Enhanced circulating half-life and hematopoietic properties of a human granulocyte colony-stimulating factor (G-CSF)-immunoglobulin fusion protein. Experimental Hematology 32: 441-449.



About Us - Technology - Products - People - News - Careers - Contact Us

Copyright © 2009 - 2016. Bolder BioTechnology, Inc. All Rights Reserved.
Disclaimer